Advances in cosmeceutical nanotechnology for hyperpigmentation treatment

نویسندگان

چکیده

Abstract Hyperpigmentation is a common and major skin problem that affects people of all types. Despite the availability various depigmentation active ingredients for hyperpigmentation disorder, none them are completely satisfactory due to their poor permeability through layer significant toxicity, thereby causing severe side effects such as irritative dermatitis, erythema, itching, flaking. Nanotechnology plays an important role in advancing cosmeceutical formulation by improving solubility, stability, safety, loading efficiency, dermal ingredients. The aim this review offer comprehensive discussion on application nanomaterials formulations used treat hyperpigmentation. Focus placed elucidating advantages nanotechnology can bring some hydroquinone, arbutin, kojic acid, azelaic retinoic acid improve efficacy treating Lastly, total 44 reported patents articles depigmenting compounds encapsulated nanoparticles were filed analyzed. Overall, lipid found be most widely nanomaterial Graphical abstract

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ژورنال

عنوان ژورنال: Journal of Nanoparticle Research

سال: 2022

ISSN: ['1572-896X', '1388-0764']

DOI: https://doi.org/10.1007/s11051-022-05534-z